137 human genomes from the Middle East fill gaps in human history
Paper -I Topic - 9.4 Genetic imprints in human disease, genetic screening, genetic counseling, human DNA profiling, gene mapping and genome study "The Middle East is an important region to understand human history, migrations, and evolution: it is where modern humans first expanded out of Africa, where hunter-gatherers first settled and transitioned into farmers, where the first writing systems developed, and where the first major known civilizations emerged," says Mohamed Almarri of the Wellcome Sanger Institute, UK. "However, despite this importance, the region has been historically understudied in genomic studies." By generating the most comprehensive resource of human genetic variation in the Middle East using a new sequencing technology called linked-read sequencing, the researchers were able to reconstruct the genomic history of the region with unprecedented resolution. The researchers say that some of the events recorded in the Middle Eastern genomes...